Effects of High-Dose Modified-Release Nicotinic Acid on Atherosclerosis and Vascular Function

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Effects of high-dose modified-release nicotinic acid on atherosclerosis and vascular function: a randomized, placebo-controlled, magnetic resonance imaging study.

OBJECTIVES Our aim was to determine the effects of high-dose (2 g) nicotinic acid (NA) on progression of atherosclerosis and measures of vascular function. BACKGROUND NA raises high-density lipoprotein cholesterol (HDL-C) and reduces low-density lipoprotein cholesterol and is widely used as an adjunct to statin therapy in patients with coronary artery disease. Although changes in plasma lipop...

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ژورنال

عنوان ژورنال: Journal of the American College of Cardiology

سال: 2009

ISSN: 0735-1097

DOI: 10.1016/j.jacc.2009.06.036